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Article: Neural precursor lineages specify distinct neocortical pyramidal neuron types.

Full Text (publisher's website) ; Article Metadata ; Article Data (extracted)
Tyler WA; Medalla M; Guillamon-Vivancos T; Luebke JI; Haydar TF
J. Neurosci., 2015

Inferred neuron-electrophysiology data values

Neuron Type Neuron Description Ephys Prop Extracted Value Standardized Value Content Source
Neocortex pyramidal cell layer 2-3 dorsal frontal cortex layer 2/3 Tbr2 expressing pyramidal cell ADP amplitude (mV) 0.5 0.5 (mV) Data Table
Neocortex pyramidal cell layer 2-3 dorsal frontal cortex layer 2/3 non-Tbr2 expressing pyramidal cell ADP amplitude (mV) 0.4 0.4 (mV) Data Table
Neocortex pyramidal cell layer 2-3 dorsal frontal cortex layer 2/3 non-Tbr2 expressing pyramidal cell AHP amplitude (mV) -12.7 12.7 (mV) Data Table
Neocortex pyramidal cell layer 2-3 dorsal frontal cortex layer 2/3 Tbr2 expressing pyramidal cell AHP amplitude (mV) -11.5 11.5 (mV) Data Table
Neocortex pyramidal cell layer 2-3 dorsal frontal cortex layer 2/3 Tbr2 expressing pyramidal cell AHP duration (ms) 41.4 41.4 (ms) Data Table
Neocortex pyramidal cell layer 2-3 dorsal frontal cortex layer 2/3 non-Tbr2 expressing pyramidal cell AHP duration (ms) 42.5 42.5 (ms) Data Table
Neocortex pyramidal cell layer 2-3 dorsal frontal cortex layer 2/3 Tbr2 expressing pyramidal cell fast AHP amplitude (mV) -5.3 5.3 (mV) Data Table
Neocortex pyramidal cell layer 2-3 dorsal frontal cortex layer 2/3 non-Tbr2 expressing pyramidal cell fast AHP amplitude (mV) -4.8 4.8 (mV) Data Table
Neocortex pyramidal cell layer 2-3 dorsal frontal cortex layer 2/3 Tbr2 expressing pyramidal cell firing frequency 6.88 6.88 (Hz) Data Table
Neocortex pyramidal cell layer 2-3 dorsal frontal cortex layer 2/3 non-Tbr2 expressing pyramidal cell firing frequency 6.94 6.94 (Hz) Data Table
Neocortex pyramidal cell layer 2-3 dorsal frontal cortex layer 2/3 Tbr2 expressing pyramidal cell input resistance 150.2 150.2 (MΩ) Data Table
Neocortex pyramidal cell layer 2-3 dorsal frontal cortex layer 2/3 non-Tbr2 expressing pyramidal cell input resistance 106.6 106.6 (MΩ) Data Table
Neocortex pyramidal cell layer 2-3 dorsal frontal cortex layer 2/3 Tbr2 expressing pyramidal cell medium AHP amplitude (mV) -6.7 6.7 (mV) Data Table
Neocortex pyramidal cell layer 2-3 dorsal frontal cortex layer 2/3 non-Tbr2 expressing pyramidal cell medium AHP amplitude (mV) -7.8 7.8 (mV) Data Table
Neocortex pyramidal cell layer 2-3 dorsal frontal cortex layer 2/3 Tbr2 expressing pyramidal cell membrane time constant (ms) 18.7 18.7 (ms) Data Table
Neocortex pyramidal cell layer 2-3 dorsal frontal cortex layer 2/3 non-Tbr2 expressing pyramidal cell membrane time constant (ms) 16.4 16.4 (ms) Data Table
Neocortex pyramidal cell layer 2-3 dorsal frontal cortex layer 2/3 non-Tbr2 expressing pyramidal cell resting membrane potential (mV) -69.5 -69.5 (mV) Data Table
Neocortex pyramidal cell layer 2-3 dorsal frontal cortex layer 2/3 Tbr2 expressing pyramidal cell resting membrane potential (mV) -66.2 -66.2 (mV) Data Table
Neocortex pyramidal cell layer 2-3 dorsal frontal cortex layer 2/3 non-Tbr2 expressing pyramidal cell rheobase (pA) 205.0 205.0 (pA) Data Table
Neocortex pyramidal cell layer 2-3 dorsal frontal cortex layer 2/3 Tbr2 expressing pyramidal cell rheobase (pA) 141.2 141.2 (pA) Data Table
Neocortex pyramidal cell layer 2-3 dorsal frontal cortex layer 2/3 non-Tbr2 expressing pyramidal cell sag amplitude (mV) 1.2 1.2 (mV) Data Table
Neocortex pyramidal cell layer 2-3 dorsal frontal cortex layer 2/3 Tbr2 expressing pyramidal cell sag amplitude (mV) 2.5 2.5 (mV) Data Table
Neocortex pyramidal cell layer 2-3 dorsal frontal cortex layer 2/3 Tbr2 expressing pyramidal cell spike amplitude (pA) 82.4 -- Data Table
Neocortex pyramidal cell layer 2-3 dorsal frontal cortex layer 2/3 non-Tbr2 expressing pyramidal cell spike amplitude (pA) 81.3 -- Data Table
Neocortex pyramidal cell layer 2-3 dorsal frontal cortex layer 2/3 non-Tbr2 expressing pyramidal cell spike half-width (ms) 2.2 2.2 (ms) Data Table
Neocortex pyramidal cell layer 2-3 dorsal frontal cortex layer 2/3 Tbr2 expressing pyramidal cell spike half-width (ms) 2.1 2.1 (ms) Data Table
Neocortex pyramidal cell layer 2-3 dorsal frontal cortex layer 2/3 non-Tbr2 expressing pyramidal cell spike threshold (mV) -32.9 -32.9 (mV) Data Table
Neocortex pyramidal cell layer 2-3 dorsal frontal cortex layer 2/3 Tbr2 expressing pyramidal cell spike threshold (mV) -36.1 -36.1 (mV) Data Table

Report miscurated data

Metadata values

Experimental condition Value
Species Mice
ElectrodeType Patch-clamp
Strain Mice, Transgenic
RecTemp 20.0 - 24.0
PrepType in vitro
InternalSolution 5.0
ExternalSolution 5.0
JxnPotential Unreported
AnimalAge 21.0
internal_0_pH 7.4
internal_0_Mg 4.0
internal_0_Na 10.3
internal_0_K 122.0
internal_0_GTP 0.3
internal_0_ATP 2.0
internal_0_EGTA 5.0
internal_0_HEPES 10.0
internal_0_Cl 4.0
external_0_pH 7.4
external_0_Mg 1.3
external_0_Na 149.0
external_0_K 3.0
external_0_Cl 132.6
external_0_Ca 2.5
external_0_glucose 10.0

Data table listing

Data Table Article Title Authors Journal Year Table needs expert? Ephys table mentions Curated by Times validated
46711 Neural precursor lineages specify distinct neocortical pyramidal neuron types. Tyler WA; Medalla M; Guillamon-Vivancos T; Luebke JI; Haydar TF J. Neurosci. 2015 False 14 Shreejoy Tripathy, Athanasios Kritharis, 2