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Article: Selective suppression of excitatory synapses on GABAergic interneurons by norepinephrine in juvenile rat prefrontal cortical microcircuitry.

Full Text (publisher's website) ; Article Metadata ; Article Data (extracted)
Wang HX; Waterhouse BD; Gao WJ
Neuroscience, 2013

Inferred neuron-electrophysiology data values

Neuron Type Neuron Description Ephys Prop Extracted Value Standardized Value Content Source
Neocortex pyramidal cell layer 5-6 Prefrontal cortex layer 5 excitatory pyramidal neurons projecting to layer 5 excitatory pyramidal neurons input resistance (MΩ) 135.0 ± 48.9 (12) 135.0 (MΩ) Data Table
Neocortex pyramidal cell layer 5-6 Prefrontal cortex layer 5 excitatory pyramidal neurons projecting to fast-spiking GABAergic interneurons input resistance (MΩ) 112.0 ± 16.3 (7) 112.0 (MΩ) Data Table
Neocortex pyramidal cell layer 5-6 Prefrontal cortex inhibitory fast-spiking GABAergic interneurons projecting to layer 5 excitatory pyramidal neurons input resistance (MΩ) 200.0 ± 31.6 (7) 200.0 (MΩ) Data Table
Neocortex pyramidal cell layer 5-6 Prefrontal cortex layer 5 excitatory pyramidal neurons projecting to layer 5 excitatory pyramidal neurons membrane time constant (ms) 26.5 ± 1.33 (12) 26.5 (ms) Data Table
Neocortex pyramidal cell layer 5-6 Prefrontal cortex layer 5 excitatory pyramidal neurons projecting to fast-spiking GABAergic interneurons membrane time constant (ms) 29.5 ± 3.15 (7) 29.5 (ms) Data Table
Neocortex pyramidal cell layer 5-6 Prefrontal cortex inhibitory fast-spiking GABAergic interneurons projecting to layer 5 excitatory pyramidal neurons membrane time constant (ms) 7.55 ± 1.36 (7) 7.55 (ms) Data Table
Neocortex pyramidal cell layer 5-6 Prefrontal cortex layer 5 excitatory pyramidal neurons projecting to layer 5 excitatory pyramidal neurons resting membrane potential (mV) -65.7 ± 5.1 (12) -65.7 (mV) Data Table
Neocortex pyramidal cell layer 5-6 Prefrontal cortex layer 5 excitatory pyramidal neurons projecting to fast-spiking GABAergic interneurons resting membrane potential (mV) -67.9 ± 2.04 (7) -67.9 (mV) Data Table
Neocortex pyramidal cell layer 5-6 Prefrontal cortex inhibitory fast-spiking GABAergic interneurons projecting to layer 5 excitatory pyramidal neurons resting membrane potential (mV) -70.0 ± 1.74 (7) -70.0 (mV) Data Table
Neocortex pyramidal cell layer 5-6 Prefrontal cortex inhibitory fast-spiking GABAergic interneurons projecting to layer 5 excitatory pyramidal neurons spike half-width (ms) 0.46 ± 0.12 (7) 0.46 (ms) Data Table
Neocortex pyramidal cell layer 5-6 Prefrontal cortex layer 5 excitatory pyramidal neurons projecting to layer 5 excitatory pyramidal neurons spike half-width (ms) 2.24 ± 0.25 (12) 2.24 (ms) Data Table
Neocortex pyramidal cell layer 5-6 Prefrontal cortex layer 5 excitatory pyramidal neurons projecting to fast-spiking GABAergic interneurons spike half-width (ms) 1.79 ± 0.17 (7) 1.79 (ms) Data Table
Neocortex pyramidal cell layer 5-6 Prefrontal cortex layer 5 excitatory pyramidal neurons projecting to layer 5 excitatory pyramidal neurons spike threshold (mV) -2.6 ± 1.23 (12) -- Data Table
Neocortex pyramidal cell layer 5-6 Prefrontal cortex layer 5 excitatory pyramidal neurons projecting to fast-spiking GABAergic interneurons spike threshold (mV) -44.2 ± 1.88 (7) -44.2 (mV) Data Table
Neocortex pyramidal cell layer 5-6 Prefrontal cortex inhibitory fast-spiking GABAergic interneurons projecting to layer 5 excitatory pyramidal neurons spike threshold (mV) -5.2 ± 1.12 (7) -5.2 (mV) Data Table

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Metadata values

Experimental condition Value
Species Rats
ElectrodeType Patch-clamp
Strain Rats, Sprague-Dawley
RecTemp 35.0 - 36.0
ExternalSolution 5.0
InternalSolution 5.0
PrepType in vitro
AnimalAge 20.0 - 23.0
JxnOffset 9.0
JxnPotential Not corrected
internal_0_pH 7.25
internal_0_Mg 4.0
internal_0_K 120.0
internal_0_ATP 4.0
internal_0_EGTA 0.2
internal_0_HEPES 10.0
internal_0_Cl 7.0
internal_0_Ca 0.5
external_0_Mg 1.0
external_0_Na 155.25
external_0_K 2.5
external_0_Cl 134.5
external_0_Ca 2.0
external_0_glucose 10.0

Data table listing

Data Table Article Title Authors Journal Year Table needs expert? Ephys table mentions Curated by Times validated
47651 Selective suppression of excitatory synapses on GABAergic interneurons by norepinephrine in juvenile rat prefrontal cortical microcircuitry. Wang HX; Waterhouse BD; Gao WJ Neuroscience 2013 False 5 Nathalie Binnion, Brenna Li, Athanasios Kritharis, 1