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Article: Temporal lobe epilepsy induces intrinsic alterations in Na channel gating in layer II medial entorhinal cortex neurons.

Full Text (publisher's website) ; Article Metadata ; Article Data (extracted)
Hargus NJ; Merrick EC; Nigam A; Kalmar CL; Baheti AR; Bertram EH; Patel MK
Neurobiol. Dis., 2011

Inferred neuron-electrophysiology data values

Neuron Type Neuron Description Ephys Prop Extracted Value Standardized Value Content Source
Medial entorhinal cortex layer II stellate cell ADP amplitude (mV) 2.2 ± 0.3 (18) 2.2 (mV) Data Table
Medial entorhinal cortex layer II stellate cell fast AHP amplitude (mV) 6.1 ± 0.6 (18) 6.1 (mV) Data Table
Medial entorhinal cortex layer II stellate cell input resistance (mΩ) 53.5 ± 3.1 (18) 53.5 (MΩ) Data Table
Medial entorhinal cortex layer II stellate cell medium AHP amplitude (mV) 10.9 ± 0.5 (18) 10.9 (mV) Data Table
Medial entorhinal cortex layer II stellate cell resting membrane potential (mV) -60.2 ± 1.1 (18) -60.2 (mV) Data Table
Medial entorhinal cortex layer II stellate cell spike amplitude (mV) 81.7 ± 2.1 (18) 81.7 (mV) Data Table
Medial entorhinal cortex layer II stellate cell spike half-width (ms) 0.79 ± 0.03 (18) 0.79 (ms) Data Table
Medial entorhinal cortex layer II stellate cell spike max rise slope 248.9 ± 11.0 (18) 248.9 (mV/ms) Data Table
Medial entorhinal cortex layer II stellate cell spike threshold (mV) -42.9 ± 0.5 (18) -42.9 (mV) Data Table
Other Medial entorhinal cortex layer 2 non-stellate cell ADP amplitude (mV) 0.3 ± 0.1 (14) 0.3 (mV) Data Table
Other Medial entorhinal cortex layer 2 non-stellate cell fast AHP amplitude (mV) 7.9 ± 0.5 (14) 7.9 (mV) Data Table
Other Medial entorhinal cortex layer 2 non-stellate cell input resistance (mΩ) 49.3 ± 3.0 (14) 49.3 (MΩ) Data Table
Other Medial entorhinal cortex layer 2 non-stellate cell medium AHP amplitude (mV) 11.9 ± 0.6 (14) 11.9 (mV) Data Table
Other Medial entorhinal cortex layer 2 non-stellate cell resting membrane potential (mV) -61.5 ± 0.9 (14) -61.5 (mV) Data Table
Other Medial entorhinal cortex layer 2 non-stellate cell spike amplitude (mV) 79.4 ± 2.4 (14) 79.4 (mV) Data Table
Other Medial entorhinal cortex layer 2 non-stellate cell spike half-width (ms) 0.84 ± 0.04 (14) 0.84 (ms) Data Table
Other Medial entorhinal cortex layer 2 non-stellate cell spike max rise slope 255.7 ± 13.0 (14) 255.7 (mV/ms) Data Table
Other Medial entorhinal cortex layer 2 non-stellate cell spike threshold (mV) -41.9 ± 0.6 (14) -41.9 (mV) Data Table

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Metadata values

Experimental condition Value
Species Rats
ElectrodeType Patch-clamp
Strain Rats, Sprague-Dawley
PrepType in vitro
InternalSolution 5.0
internal_1_pH 7.3
internal_1_Mg 2.0
internal_1_Na 8.3
internal_1_Cl 4.0
ExternalSolution 5.0
internal_2_pH 7.3
internal_2_Mg 4.0
internal_2_Ca 1.6
internal_2_Na 48.3
internal_2_Cl 161.6
internal_3_pH 7.4
internal_3_Mg 2.0
internal_3_Ca 2.0
internal_3_Na 158.0
internal_3_Cl 130.7
internal_3_K 3.0
JxnPotential Unreported
AnimalWeight 250.0 - 300.0
RecTemp 32.0
internal_0_pH 7.2
internal_0_Mg 2.0
internal_0_Na 18.3
internal_0_K 121.0
internal_0_GTP 0.3
internal_0_ATP 4.0
internal_0_EGTA 0.5
internal_0_HEPES 10.0
internal_0_Cl 14.0
external_0_Mg 1.0
external_0_Na 151.25
external_0_K 2.5
external_0_Cl 133.5
external_0_Ca 2.0
external_0_glucose 10.0

Data table listing

Data Table Article Title Authors Journal Year Table needs expert? Ephys table mentions Curated by Times validated
48110 Temporal lobe epilepsy induces intrinsic alterations in Na channel gating in layer II medial entorhinal cortex neurons. Hargus NJ; Merrick EC; Nigam A; Kalmar CL; Baheti AR; Bertram EH; Patel MK Neurobiol. Dis. 2011 False 9 Nathalie Binnion, James liu, 1
48111 Temporal lobe epilepsy induces intrinsic alterations in Na channel gating in layer II medial entorhinal cortex neurons. Hargus NJ; Merrick EC; Nigam A; Kalmar CL; Baheti AR; Bertram EH; Patel MK Neurobiol. Dis. 2011 False 0 None