AboutNeuron TypesElectrophysiology PropertiesArticlesFAQsData/APIGet Involved

Article: TRPA1 channels mediate cold temperature sensing in mammalian vagal sensory neurons: pharmacological and genetic evidence.

Full Text (publisher's website) ; Article Metadata ; Article Data (extracted)
Fajardo O; Meseguer V; Belmonte C; Viana F
J. Neurosci., 2008


Table 1.

Electrophysiological properties of cold-sensitive and cold-insensitive adult rat cultured nodose neurons

Cold sensitive (n = 7) Cold insensitive (n = 8) p value
Input resistance 340 ± 121 MΩ 317 ± 79 M NS
Resting membrane potential −56 ± 3 mV −56 ± 3 mV NS
Firing threshold −42 ± 1 mV −43 ± 1 mV NS
Rheobase 52 ± 14 pA 58 ± 13 pA NS
Action potential amplitude 98 ± 5 mV 101 ± 4 mV NS
Action potential duration 1.00 ± 0.09 ms 1.19 ± 0.04 ms NS

  • Neurons were recorded in the perforated-patch current-clamp configuration. Input resistance was measured from the slope of peak voltage response to a series of negative current steps. Spike duration was measured at half amplitude.


Report miscurated data

Inferred neuron-electrophysiology data values

Neuron Type Neuron Description Ephys Prop Extracted Value Standardized Value Content Source
DRG temperature cell spike threshold -42.0 ± 1.0 (7) -42.0 (mV) Data Table
Dorsal root ganglion cell spike threshold -43.0 ± 1.0 (8) -43.0 (mV) Data Table
DRG temperature cell rheobase 52.0 ± 14.0 (7) 52.0 (pA) Data Table
Dorsal root ganglion cell rheobase 58.0 ± 13.0 (8) 58.0 (pA) Data Table
DRG temperature cell spike amplitude 98.0 ± 5.0 (7) 98.0 (mV) Data Table
Dorsal root ganglion cell spike amplitude 101.0 ± 4.0 (8) 101.0 (mV) Data Table
DRG temperature cell input resistance 340.0 ± 121.0 (7) 340.0 (MΩ) Data Table
DRG temperature cell spike half-width 1.0 ± 0.09 (7) 1.0 (ms) Data Table
Dorsal root ganglion cell spike half-width 1.19 ± 0.04 (8) 1.19 (ms) Data Table
Dorsal root ganglion cell input resistance 317.0 ± 79.0 (8) 317.0 (MΩ) Data Table
DRG temperature cell resting membrane potential -56.0 ± 3.0 (7) -56.0 (mV) Data Table
Dorsal root ganglion cell resting membrane potential -56.0 ± 3.0 (8) -56.0 (mV) Data Table