Article: Dopamine and corticotropin-releasing factor synergistically alter basolateral amygdala-to-medial prefrontal cortex synaptic transmission: functional switch after chronic cocaine administration.
Full Text (publisher's website) ; Article Metadata ; Article Data (extracted) Orozco-Cabal L; Liu J; Pollandt S; Schmidt K; Shinnick-Gallagher P; Gallagher JP J. Neurosci., 2008
Table 1.
Comparison of membrane electrical properties of layer V pyramidal neurons of the PL cortex recorded intracellularly from chronic cocaine- and saline-treated/control rats
Saline/control group | Cocaine-treated group | ||||
---|---|---|---|---|---|
Mean | SEM | Mean | SEM | pa | |
RMP (mV) | −65.9 | 0.3 | −62.3 | 1.2 | <0.01 |
Rm (MΩ) | 80.3 | 2.8 | 87.0 | 3.3 | <0.05 |
τ (ms) | 6.7 | 0.2 | 7.4 | 0.2 | <0.01 |
n | 111 | 109 |
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RMP, Resting membrane potential; Rm, membrane resistance; τ, membrane time constant.
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↵aWald-Wolfowltz test.
Inferred neuron-electrophysiology data values
Neuron Type | Neuron Description | Ephys Prop | Extracted Value | Standardized Value | Content Source |
---|---|---|---|---|---|
Neocortex pyramidal cell layer 5-6 | Layer 5 medial prefrontal cortex prelimbic pyramidal neurons | membrane time constant (ms) | 6.7 (111) | 6.7 (ms) | Data Table |
Neocortex pyramidal cell layer 5-6 | Layer 5 medial prefrontal cortex prelimbic pyramidal neurons | resting membrane potential (mV) | -65.9 (111) | -65.9 (mV) | Data Table |
Neocortex pyramidal cell layer 5-6 | Layer 5 medial prefrontal cortex prelimbic pyramidal neurons | input resistance (MΩ) | 80.3 (111) | 80.3 (MΩ) | Data Table |