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Article: Rac1 and rac3 GTPases control synergistically the development of cortical and hippocampal GABAergic interneurons.

Full Text (publisher's website) ; Article Metadata ; Article Data (extracted)
Vaghi V; Pennucci R; Talpo F; Corbetta S; Montinaro V; Barone C; Croci L; Spaiardi P; Consalez GG; Biella G; de Curtis I
Cereb. Cortex, 2014


Table 1

Passive and discharge properties measured in CA3 pyramidal neurons from control and double KO (dKO) mice.

Capacity (pF) INa+ peak (pA) Resting potential (mV) Input Resistance (MΩ) Membrane time constant (ms) Spike Threshold (mV) Spike amplitude (mV) Spike duration (ms)
Control (n = 17) 86.1 ± 4.1 11 224 ± 835 -72.1 ± 2.3 462 ± 40 56.0 ± 4.8 -54.2 ± 1.5 83.0 ± 2.7 2.0 ± 0.1
dKO (n = 15) 84.6 ± 3.6 11 084 ± 756 -75.3 ± 1.5 506 ± 50 57.0 ± 4.7 -50.8 ± 0.8 81.8 ± 1.9 2.0 ± 0.1

  • Values are means ± SEM. No significant differences are detected.


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Inferred neuron-electrophysiology data values

Neuron Type Neuron Description Ephys Prop Extracted Value Standardized Value Content Source
Hippocampus CA3 pyramidal cell cell capacitance (pF) 86.1 ± 4.1 (17) 86.1 (pF) Data Table
Hippocampus CA3 pyramidal cell resting membrane potential (mV) -72.1 ± 2.3 (17) -72.1 (mV) Data Table
Hippocampus CA3 pyramidal cell input resistance (MΩ) 462.0 ± 40.0 (17) 462.0 (MΩ) Data Table
Hippocampus CA3 pyramidal cell membrane time constant (ms) 56.0 ± 4.8 (17) 56.0 (ms) Data Table
Hippocampus CA3 pyramidal cell spike threshold (mV) -54.2 ± 1.5 (17) -54.2 (mV) Data Table
Hippocampus CA3 pyramidal cell spike amplitude (mV) 83.0 ± 2.7 (17) 83.0 (mV) Data Table
Hippocampus CA3 pyramidal cell spike width (ms) 2.0 ± 0.1 (17) 2.0 (ms) Data Table