Article: Role of gap junctions in synchronized neuronal oscillations in the inferior olive.

TABLE 1.Effects of 18 ${beta}$ -GA on physiological properties of IO neurons



	Control	18 ${beta}$ -GA

Number of indirectly labeled cells per Neurobiotin injection^*	12.0 ± 1.1 (6)	0.2 ± 0.1 (9)
Input resistance, MΩ^†	33.2 ± 3.3 (8)	38.4 ± 4.0 (8)
Time constant,^‡ ms^§	8.6 ± 0.6 (8)	6.7 ± 0.6 (8)
Membrane capacitance,^¶ nF^†	0.27 ± 0.06 (8)	0.18 ± 0.04 (8)
Na⁺ spike amplitude, mV	78 ± 1.1 (29)	78 ± 1.3 (15)
LTS amplitude, mV	24.6 ± 1.0 (29)	24.9 ± 1.3 (15)
HTS amplitude, mV	59.8 ± 2.4 (29)	66.0 ± 1.7 (13)
HTS duration, ms^**	3.7 ± 0.3 (29)	6.7 ± 0.5 (13)
Oscillation frequency, Hz	6.0 ± 0.5 (31)	6.9 ± 0.4 (23)
Oscillations amplitude, mV	7.4 ± 0.7 (31)	7.1 ± 1.2 (23)

Data are shown as mean ± SE. Numbers in parentheses indicate the number of neurons tested.

^* P < 0.0001 compared with control (unpaired 2-tailed Student's t-test).

^† P < 0.002 compared with control (paired 2-tailed Student's t-test).

^‡ Time constant was estimated using a single exponential fit of the charging current.

^§ P < 0.001 compared with control (paired 2-tailed Student's t-test).

^¶ Capacitance was determined by dividing time constant by input resistance.

^** P < 0.001 compared with control (unpaired 2-tailed Student's t-test). 18 ${beta}$ -GA, 18 ${beta}$ -glycyrrhetinic acid.

Inferred neuron-electrophysiology data values

Neuron Type	Ephys Prop	Extracted Value	Standardized Value	Content Source
Inferior olive neuron	input resistance	33.2 ± 3.3 (8)	33.2 (MΩ)	Data Table
Inferior olive neuron	membrane time constant	8.6 ± 0.6 (8)	8.6 (ms)	Data Table
Inferior olive neuron	cell capacitance	0.27 ± 0.06 (8)	--	Data Table
Inferior olive neuron	spike amplitude from resting (mV)	78.0 ± 1.1 (29)	78.0 (mV)	Data Table