Table 1. Properties of immature apical-coil IHCs from SK2 mutant mice
| +/+ and +/Δ (P2–P4) | Δ/Δ (P2–P4) | |
|---|---|---|
| Steady-state activation and inactivation values (see Marcotti et al. 2003a for comparisons with normal CD-1 mice) are from fits using a first-order Boltzmann equation. Values are means ± s.e.m.; number of hair cells is in parentheses. None of the values shown above were significantly different between control and mutant IHCs. | ||
| Membrane capacitance (pF) | 7.4 ± 0.2 (21) | 7.3 ± 0.3 (15) |
| Resting potential (mV) | −57.5 ± 0.8 (31) | −56.5 ± 1.1 (11) |
| IK1 at −124 mV (pA) | −112 ± 12 (10) | −117 ± 20 (7) |
| IK,neo at 0 mV (nA) | 3.1 ± 0.1 (12) | 3.1 ± 0.3 (12) |
| g at −84 mV (nS) | 1.2 ± 0.1 (13) | 1.5 ± 0.3 (8) |
| IK,neo: steady-state activation | ||
| Vhalf (mV) | −32.9 ± 0.7 (12) | −33.5 ± 1.6 (7) |
| Slope factor, S (mV) | 6.6 ± 0.2 (12) | 6.6 ± 0.5 (7) |
| IK,neo: steady-state inactivation | ||
| Vhalf (mV) | −45.1 ± 3.3 (5) | −39.4 ± 6.6 (3) |
| Slope factor, S (mV) | 16.2 ± 1.4 (5) | 12.2 ± 1.5 (3) |