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Article: Mechanisms and consequences of action potential burst firing in rat neocortical pyramidal neurons.

Full Text (publisher's website) ; Article Metadata ; Article Data (extracted)
Williams SR; Stuart GJ
J. Physiol. (Lond.), 1999


Table 1 Subthreshold electrophysiological properties of layer 5 pyramidal neurons
All cells Regular firing Burst firing Weak burst firing Strong burst firing
Number of cells 61 26 (43 %) 35 (57 %) 9 (14 %) 26 (43 %)
Membrane potential (mV) −63.4 ± 0.4 −63.2 ± 0.6 −63.5 ± 0.52 −65.2 ± 1.1 −62.9 ± 0.5
−63 −63 −64 −66 −63
Minimum 3rd quadrant 21.1 ± 1.2 24.4 ± 2.1 18.5 ± 1.3* 24.6 ± 3.2 16.3 ± 0.9†‡
peak slope resistance (MΩ) 17.6 22.2 16.6 24.1 15.8
Maximum 3rd quadrant 28.2 ± 1.7 34.6 ± 3.1 23.2 ± 1.5* 29.8 ± 2.45 21.0 ± 1.6 ‡
peak slope resistance (MΩ) 25.5 31.1 20.6 30.0 18.8
Minimum 3rd quadrant steady-state slope 17.0 ± 1.1 19.7 ± 1.8 15.0 ± 1.2 20.8 ± 3.6 12.8 ± 0.8†‡
resistance (MΩ) 15.3 18.3 3.9 19.3 12.6
Maximum 3rd quadrant steady-state slope 21.2 ± 1.4 26.1 ± 2.6 17.5 ± 1.2* 22.82 ± 2.0 15.8 ± 1.3‡
resistance (MΩ) 18.98 24.5 16.1 22.4 13.6
Minimum 1st quadrant 46.2 ± 4.4 61.1 ± 9.2 36.3 ± 3.1* 49.7 ± 5.2 31.3 ± 3.3†‡
peak slope resistance (MΩ) 38.9 54.0 31.8 47.1 27.6
1st quadrant steady-state 32.2 ± 2.4 41.2 ± 3.9 26.4 ± 2.5* 38.1 ± 4.1 22.1 ± 2.6†‡
slope resistance (MΩ) 28.58 39.8 22.5 37.3 17.9
Subthreshold transient 4.3 ± 0.2 3.6 ± 0.3 4.75 ± 0.3 2.9 ± 0.3 5.3 ± 0.3†‡
depolarising potential (mV) 4.3 3.3 4.8 2.7 5.5

  • Numerical values are given as means ±s.e.m. (top line) and median (lower line).

  • ↵* Significant difference between burst and regular firing cells (ANOVA).

  • ↵† Significant difference between weak burst and strong burst firing cells (ANOVA).

  • ↵‡ Significant difference between regular and strong burst firing cells (ANOVA).


Report miscurated data

Inferred neuron-electrophysiology data values

Neuron Type Neuron Description Ephys Prop Extracted Value Standardized Value Content Source
Neocortex pyramidal cell layer 5-6 Layer 5 somatosensory cortex burst firing pyramidal neurons resting membrane potential (mV) -63.5 ± 0.52 -- Data Table
Neocortex pyramidal cell layer 5-6 Layer 5 somatosensory cortex weak burst firing pyramidal neurons resting membrane potential (mV) -65.2 ± 1.1 -- Data Table
Neocortex pyramidal cell layer 5-6 Layer 5 somatosensory cortex strong burst firing pyramidal neurons resting membrane potential (mV) -62.9 ± 0.5 -- Data Table
Neocortex pyramidal cell layer 5-6 Layer 5 somatosensory cortex pyramidal neurons input resistance (MΩ) 15.3 15.3 (MΩ) Data Table
Neocortex pyramidal cell layer 5-6 Layer 5 somatosensory cortex regular firing pyramidal neurons input resistance (MΩ) 18.3 -- Data Table
Neocortex pyramidal cell layer 5-6 Layer 5 somatosensory cortex burst firing pyramidal neurons input resistance (MΩ) 3.9 -- Data Table
Neocortex pyramidal cell layer 5-6 Layer 5 somatosensory cortex weak burst firing pyramidal neurons input resistance (MΩ) 19.3 -- Data Table
Neocortex pyramidal cell layer 5-6 Layer 5 somatosensory cortex strong burst firing pyramidal neurons input resistance (MΩ) 12.6 -- Data Table
Neocortex pyramidal cell layer 5-6 Layer 5 somatosensory cortex pyramidal neurons input resistance (MΩ) 18.98 18.98 (MΩ) Data Table
Neocortex pyramidal cell layer 5-6 Layer 5 somatosensory cortex regular firing pyramidal neurons input resistance (MΩ) 24.5 -- Data Table
Neocortex pyramidal cell layer 5-6 Layer 5 somatosensory cortex burst firing pyramidal neurons input resistance (MΩ) 16.1 -- Data Table
Neocortex pyramidal cell layer 5-6 Layer 5 somatosensory cortex weak burst firing pyramidal neurons input resistance (MΩ) 22.4 -- Data Table
Neocortex pyramidal cell layer 5-6 Layer 5 somatosensory cortex strong burst firing pyramidal neurons input resistance (MΩ) 13.6 -- Data Table
Neocortex pyramidal cell layer 5-6 Layer 5 somatosensory cortex pyramidal neurons resting membrane potential (mV) -63.4 ± 0.4 -63.4 (mV) Data Table
Neocortex pyramidal cell layer 5-6 Layer 5 somatosensory cortex regular firing pyramidal neurons resting membrane potential (mV) -63.2 ± 0.6 -- Data Table