Article: Postsynaptic action of BDNF on GABAergic synaptic transmission in the superficial layers of the mouse superior colliculus.

Full Text (publisher's website) ; Article Metadata ; Article Data (extracted)
Henneberger C; Jüttner R; Rothe T; Grantyn R
J. Neurophysiol., 2002

Table 1.

Summary of quantitative data

	bdnf⁺/⁺		bdnf−/−		PValue
	Mean	n	Mean	n	PValue
Basic properties
Input resistance, MΩ	521 ± 101	22	503 ± 91	22	n.s.
Whole cell capacitance, pF	16 ± 2	22	16 ± 4	22	n.s.
Membrane potential, mV	44.2 ± 2.1	23	44.4 ± 1.5	30	n.s
Spontaneous action potential discharge
Action potential frequency, s⁻¹	5.3 ± 0.6	32	2.5 ± 0.3	21	<0.01
Bicuculline to control ratio	1.31 ± 0.17	14	1.99 ± 0.30	11	<0.05
eIPSCs
Average peak amplitude, pA	93 ± 9	19	178 ± 23	20	<0.01
Variation of peak amplitude, CV	0.41 ± 0.03	19	0.40 ± 0.02	20	n.s.
Decay time constant τ, ms	14.3 ± 1.2	19	15.8 ± 1.2	20	n.s
sIPSCs
Average peak amplitude, pA	33 ± 2	41	46 ± 4	42	<0.001
Decay time constant τ, ms	20.4 ± 1.7	21	22.3 ± 1.7	24	n.s.
Frequency, s⁻¹	0.88 ± 0.30	21	0.81 ± 0.20	24	n.s.
mIPSCs
Average peak amplitude, pA	21.3 ± 1.9	13	33.7 ± 4.3	13	<0.05
Time to peak (20–80%), ms	1.0 ± 0.1	13	0.9 ± 0.1	13	n.s.
Decay time constant τ, ms	20.4 ± 1.5	13	22.7 ± 2.1	13	n.s.
Frequency, s⁻¹	0.11 ± 0.03	13	0.13 ± 0.04	13	n.s.
Paired-pulse ratio
25-ms interval	1.37 ± 0.19	18	1.33 ± 0.11	18	n.s.
50-ms interval	1.08 ± 0.11	18	1.17 ± 0.07	18	n.s

eIPSC, sIPSC, and mIPSC, evoked, spontaneous, and miniature inhibitory postsynaptic current.

Inferred neuron-electrophysiology data values

Neuron Type	Ephys Prop	Extracted Value	Standardized Value	Content Source
Superior colliculus superficial layer neuron	cell capacitance (pF)	16.0 ± 2.0 (22)	--	Data Table
Superior colliculus superficial layer neuron	resting membrane potential (mV)	44.2 ± 2.1 (22)	--	Data Table
Superior colliculus superficial layer neuron	firing frequency	5.3 ± 0.6 (22)	--	Data Table
Superior colliculus superficial layer neuron	input resistance	521.0 ± 101.0 (22)	--	Data Table