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Hippocampus CA1 pyramidal cell (Definition)

Electrophysiological properties of Hippocampus CA1 pyramidal cells from literature:

    Legend:
  • Reports: Blue dots indicate human-curated values; Orange dots indicate non-human curated values
  • Mean+SD: mean and standard deviation of human-curated neuron measurements
  • All neurons: mean and standard deviation computed over all neurons in database
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  • Legend: Blue dots = text-mined values human curated; Orange dots = text-mined values not human curated







































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Articles with extracted electrophysiology properties:

Article Title Authors Journal Year Electrophys values Neuron types
Hyperexcitability of distal dendrites in hippocampal pyramidal cells after chronic partial deafferentation. (NeuroElectro data) (PubMed) Cai X; Wei DS; Gallagher SE; Bagal A; Mei YA; Kao JP; Thompson SM; Tang CM J. Neurosci. 2007 4 1
A spontaneous mutation involving Kcnq2 (Kv7.2) reduces M-current density and spike frequency adaptation in mouse CA1 neurons. (NeuroElectro data) (PubMed) Otto JF; Yang Y; Frankel WN; White HS; Wilcox KS J. Neurosci. 2006 5 1
KCNQ/M channels control spike afterdepolarization and burst generation in hippocampal neurons. (NeuroElectro data) (PubMed) Yue C; Yaari Y J. Neurosci. 2004 6 1
Alterations in intrinsic membrane properties and the axon initial segment in a mouse model of Angelman syndrome. (NeuroElectro data) (PubMed) Kaphzan H; Buffington SA; Jung JI; Rasband MN; Klann E J. Neurosci. 2011 3 1
Resting and active properties of pyramidal neurons in subiculum and CA1 of rat hippocampus. (NeuroElectro data) (PubMed) Staff NP; Jung HY; Thiagarajan T; Yao M; Spruston N J. Neurophysiol. 2000 16 2
Transition to seizures in the isolated immature mouse hippocampus: a switch from dominant phasic inhibition to dominant phasic excitation. (NeuroElectro data) (PubMed) Derchansky M; Jahromi SS; Mamani M; Shin DS; Sik A; Carlen PL J. Physiol. (Lond.) 2008 15 3
Proximal persistent Na+ channels drive spike afterdepolarizations and associated bursting in adult CA1 pyramidal cells. (NeuroElectro data) (PubMed) Yue C; Remy S; Su H; Beck H; Yaari Y J. Neurosci. 2005 12 1
Extracellular calcium modulates persistent sodium current-dependent burst-firing in hippocampal pyramidal neurons. (NeuroElectro data) (PubMed) Su H; Alroy G; Kirson ED; Yaari Y J. Neurosci. 2001 6 1
Initiation of network bursts by Ca2+-dependent intrinsic bursting in the rat pilocarpine model of temporal lobe epilepsy. (NeuroElectro data) (PubMed) Sanabria ER; Su H; Yaari Y J. Physiol. (Lond.) 2001 5 1
Cholinergic stimulation enhances cytosolic calcium ion accumulation in mouse hippocampal CA1 pyramidal neurones during short action potential trains. (NeuroElectro data) (PubMed) Beier SM; Barish ME J. Physiol. (Lond.) 2000 2 1
Slow afterhyperpolarization governs the development of NMDA receptor-dependent afterdepolarization in CA1 pyramidal neurons during synaptic stimulation. (NeuroElectro data) (PubMed) Wu WW; Chan CS; Disterhoft JF J. Neurophysiol. 2004 3 1
Differences in subthreshold resonance of hippocampal pyramidal cells and interneurons: the role of h-current and passive membrane characteristics. (NeuroElectro data) (PubMed) Zemankovics R; Káli S; Paulsen O; Freund TF; Hájos N J. Physiol. (Lond.) 2010 21 3
Examining protection from anoxic depolarization by the drugs dibucaine and carbetapentane using whole-cell recording from CA1 neurons. (NeuroElectro data) (PubMed) None J. Neurophysiol. 2012 10 1
Developmental sensitivity of hippocampal interneurons to ethanol: involvement of the hyperpolarization-activated current, Ih. (NeuroElectro data) (PubMed) Yan H; Li Q; Fleming R; Madison RD; Wilson WA; Swartzwelder HS J. Neurophysiol. 2009 3 1
Heterogeneous firing behavior during ictal-like epileptiform activity in vitro. (NeuroElectro data) (PubMed) Andreasen M; Nedergaard S J. Neurophysiol. 2012 6 1
Disrupting function of FK506-binding protein 1b/12.6 induces the Ca²+-dysregulation aging phenotype in hippocampal neurons. (NeuroElectro data) (PubMed) Gant JC; Chen KC; Norris CM; Kadish I; Thibault O; Blalock EM; Porter NM; Landfield PW J. Neurosci. 2011 3 1
Cholecystokinin increases GABA release by inhibiting a resting K+ conductance in hippocampal interneurons. (NeuroElectro data) (PubMed) Miller KK; Hoffer A; Svoboda KR; Lupica CR J. Neurosci. 1997 4 1
Temporal overlap of excitatory and inhibitory afferent input in guinea-pig CA1 pyramidal cells. (NeuroElectro data) (PubMed) Karnup S; Stelzer A J. Physiol. (Lond.) 1999 8 2
Enhanced intrinsic excitability and EPSP-spike coupling accompany enriched environment-induced facilitation of LTP in hippocampal CA1 pyramidal neurons. (NeuroElectro data) (PubMed) Malik R; Chattarji S J. Neurophysiol. 2012 9 1
Group I mGluRs increase excitability of hippocampal CA1 pyramidal neurons by a PLC-independent mechanism. (NeuroElectro data) (PubMed) Ireland DR; Abraham WC J. Neurophysiol. 2002 2 1
Intracellular correlates of spatial memory acquisition in hippocampal slices: long-term disinhibition of CA1 pyramidal cells. (NeuroElectro data) (PubMed) Gusev PA; Alkon DL J. Neurophysiol. 2001 5 1
Mechanism for increased hippocampal synaptic strength following differential experience. (NeuroElectro data) (PubMed) Foster TC; Dumas TC J. Neurophysiol. 2001 3 1
Hypoxia-induced neonatal seizures diminish silent synapses and long-term potentiation in hippocampal CA1 neurons. (NeuroElectro data) (PubMed) Zhou C; Lippman JJ; Sun H; Jensen FE J. Neurosci. 2011 3 1
A functional null mutation of SCN1B in a patient with Dravet syndrome. (NeuroElectro data) (PubMed) Patino GA; Claes LR; Lopez-Santiago LF; Slat EA; Dondeti RS; Chen C; O'Malley HA; Gray CB; Miyazaki H; Nukina N; Oyama F; De Jonghe P; Isom LL J. Neurosci. 2009 10 1
Early and simultaneous emergence of multiple hippocampal biomarkers of aging is mediated by Ca2+-induced Ca2+ release. (NeuroElectro data) (PubMed) Gant JC; Sama MM; Landfield PW; Thibault O J. Neurosci. 2006 4 1
Depression of synaptic transmission by vascular endothelial growth factor in adult rat hippocampus and evidence for increased efficacy after chronic seizures. (NeuroElectro data) (PubMed) McCloskey DP; Croll SD; Scharfman HE J. Neurosci. 2005 6 1
Focal deletion of the adenosine A1 receptor in adult mice using an adeno-associated viral vector. (NeuroElectro data) (PubMed) Scammell TE; Arrigoni E; Thompson MA; Ronan PJ; Saper CB; Greene RW J. Neurosci. 2003 5 1
Elevated postsynaptic [Ca2+]i and L-type calcium channel activity in aged hippocampal neurons: relationship to impaired synaptic plasticity. (NeuroElectro data) (PubMed) Thibault O; Hadley R; Landfield PW J. Neurosci. 2001 6 1
Unique properties of NMDA receptors enhance synaptic excitation of radiatum giant cells in rat hippocampus. (NeuroElectro data) (PubMed) Kirson ED; Yaari Y J. Neurosci. 2000 10 2
Unitary IPSPs evoked by interneurons at the stratum radiatum-stratum lacunosum-moleculare border in the CA1 area of the rat hippocampus in vitro. (NeuroElectro data) (PubMed) Vida I; Halasy K; Szinyei C; Somogyi P; Buhl EH J. Physiol. (Lond.) 1998 15 3
Synaptic ionotropic glutamate receptors and plasticity are developmentally altered in the CA1 field of Fmr1 knockout mice. (NeuroElectro data) (PubMed) Pilpel Y; Kolleker A; Berberich S; Ginger M; Frick A; Mientjes E; Oostra BA; Seeburg PH J. Physiol. (Lond.) 2009 5 1
NMDA receptor-dependent long-term potentiation in mouse hippocampal interneurons shows a unique dependence on Ca(2+)/calmodulin-dependent kinases. (NeuroElectro data) (PubMed) Lamsa K; Irvine EE; Giese KP; Kullmann DM J. Physiol. (Lond.) 2007 14 2
Mechanisms of electrical coupling between pyramidal cells. (NeuroElectro data) (PubMed) Vigmond EJ; Perez Velazquez JL; Valiante TA; Bardakjian BL; Carlen PL J. Neurophysiol. 1997 2 1
Differential corticosteroid modulation of inhibitory synaptic currents in the dorsal and ventral hippocampus. (NeuroElectro data) (PubMed) Maggio N; Segal M J. Neurosci. 2009 20 1
Heterogeneous populations of cells mediate spontaneous synchronous bursting in the developing hippocampus through a frequency-dependent mechanism. (NeuroElectro data) (PubMed) Menendez de la Prida L; Sanchez-Andres JV Neuroscience 2000 16 4

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